Molecular beacons as probes of RNA unfolding under native conditions

Hybridization of fluorescent molecular beacons provides real-time detection of RNA secondary structure with high specificity. We used molecular beacons to measure folding and unfolding rates of the Tetrahymena group I ribozyme under native conditions. A molecular beacon targeted against 15 nt in the...

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Detalles Bibliográficos
Autores principales: Hopkins, Julia F., Woodson, Sarah A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253827/
https://www.ncbi.nlm.nih.gov/pubmed/16221975
http://dx.doi.org/10.1093/nar/gki877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253827/
https://www.ncbi.nlm.nih.gov/pubmed/16221975
http://dx.doi.org/10.1093/nar/gki877

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