An ES cell system for rapid, spatial and temporal analysis of gene function in vitro and in vivo

We describe a versatile genetic system for rapid analysis of mammalian gene function. In this, loss of reporter activity in a novel embryonic stem (ES) cell line enables rapid identification of targeting to the ubiquitously expressed Rosa26 locus. Subsequent regulation of gene activity is governed b...

Descripción completa

Detalles Bibliográficos
Autores principales: Mao, Junhao, Barrow, Jeffery, McMahon, Jill, Vaughan, Joe, McMahon, Andrew P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253836/
https://www.ncbi.nlm.nih.gov/pubmed/16221970
http://dx.doi.org/10.1093/nar/gni146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253836/
https://www.ncbi.nlm.nih.gov/pubmed/16221970
http://dx.doi.org/10.1093/nar/gni146

Ejemplares similares