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An ES cell system for rapid, spatial and temporal analysis of gene function in vitro and in vivo

We describe a versatile genetic system for rapid analysis of mammalian gene function. In this, loss of reporter activity in a novel embryonic stem (ES) cell line enables rapid identification of targeting to the ubiquitously expressed Rosa26 locus. Subsequent regulation of gene activity is governed b...

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Detalles Bibliográficos
Autores principales:	Mao, Junhao, Barrow, Jeffery, McMahon, Jill, Vaughan, Joe, McMahon, Andrew P.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2005
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253836/ https://www.ncbi.nlm.nih.gov/pubmed/16221970 http://dx.doi.org/10.1093/nar/gni146

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