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A highly sensitive selection method for directed evolution of homing endonucleases
Homing endonucleases are enzymes that catalyze DNA sequence specific double-strand breaks and can significantly stimulate homologous recombination at these breaks. These enzymes have great potential for applications such as gene correction in gene therapy or gene alteration in systems biology and me...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253837/ https://www.ncbi.nlm.nih.gov/pubmed/16214805 http://dx.doi.org/10.1093/nar/gni148 |