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The Geographic Spread of the CCR5 Δ32 HIV-Resistance Allele

The Δ32 mutation at the CCR5 locus is a well-studied example of natural selection acting in humans. The mutation is found principally in Europe and western Asia, with higher frequencies generally in the north. Homozygous carriers of the Δ32 mutation are resistant to HIV-1 infection because the mutat...

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Detalles Bibliográficos
Autores principales: Novembre, John, Galvani, Alison P, Slatkin, Montgomery
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1255740/
https://www.ncbi.nlm.nih.gov/pubmed/16216086
http://dx.doi.org/10.1371/journal.pbio.0030339