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Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro

Certain monoclonal antibodies (mAbs) to type II collagen (CII) induce arthritis in vivo after passive transfer and have adverse effects on chondrocyte cultures and inhibit self assembly of collagen fibrils in vitro. We have examined whether such mAbs have detrimental effects on pre-existing cartilag...

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Detalles Bibliográficos
Autores principales: Crombie, Duncan E, Turer, Muhammed, Zuasti, Beltzane Biurrun, Wood, Bayden, McNaughton, Don, Nandakumar, Kutty Selva, Holmdahl, Rikard, Van Damme, Marie-Paule, Rowley, Merrill J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257420/
https://www.ncbi.nlm.nih.gov/pubmed/16207334
http://dx.doi.org/10.1186/ar1766