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Rheumatoid arthritis as a hyper-endoplasmic reticulum-associated degradation disease

We introduce Synoviolin as a novel pathogenic factor in rheumatoid arthritis (RA). Experimental studies indicate that this endoplasmic reticulum (ER)-resident E3 ubiquitin ligase has important functions in the ER-associated degradation (ERAD) system, an essential system for ER homeostasis. Overexpre...

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Detalles Bibliográficos
Autores principales: Yamasaki, Satoshi, Yagishita, Naoko, Tsuchimochi, Kaneyuki, Nishioka, Kusuki, Nakajima, Toshihiro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257448/
https://www.ncbi.nlm.nih.gov/pubmed/16207344
http://dx.doi.org/10.1186/ar1808