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Explicit equilibrium modeling of transcription-factor binding and gene regulation

We have developed a computational model that predicts the probability of transcription factor binding to any site in the genome. GOMER (generalizable occupancy model of expression regulation) calculates binding probabilities on the basis of position weight matrices, and incorporates the effects of c...

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Detalles Bibliográficos
Autores principales: Granek, Joshua A, Clarke, Neil D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257470/
https://www.ncbi.nlm.nih.gov/pubmed/16207358
http://dx.doi.org/10.1186/gb-2005-6-10-r87