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Explicit equilibrium modeling of transcription-factor binding and gene regulation
We have developed a computational model that predicts the probability of transcription factor binding to any site in the genome. GOMER (generalizable occupancy model of expression regulation) calculates binding probabilities on the basis of position weight matrices, and incorporates the effects of c...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257470/ https://www.ncbi.nlm.nih.gov/pubmed/16207358 http://dx.doi.org/10.1186/gb-2005-6-10-r87 |