Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis

We describe a large-scale random approach termed reduced representation bisulfite sequencing (RRBS) for analyzing and comparing genomic methylation patterns. BglII restriction fragments were size-selected to 500–600 bp, equipped with adapters, treated with bisulfite, PCR amplified, cloned and sequen...

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Detalles Bibliográficos
Autores principales: Meissner, Alexander, Gnirke, Andreas, Bell, George W., Ramsahoye, Bernard, Lander, Eric S., Jaenisch, Rudolf
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1258174/
https://www.ncbi.nlm.nih.gov/pubmed/16224102
http://dx.doi.org/10.1093/nar/gki901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1258174/
https://www.ncbi.nlm.nih.gov/pubmed/16224102
http://dx.doi.org/10.1093/nar/gki901

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