The RING finger ATPase Rad5p of Saccharomyces cerevisiae contributes to DNA double-strand break repair in a ubiquitin-independent manner

Tolerance to replication-blocking DNA lesions is achieved by means of ubiquitylation of PCNA, the processivity clamp for replicative DNA polymerases, by components of the RAD6 pathway. In the yeast Saccharomyces cerevisiae the ubiquitin ligase (E3) responsible for polyubiquitylation of the clamp is...

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Detalles Bibliográficos
Autores principales: Chen, Shuhua, Davies, Adelina A., Sagan, Daniel, Ulrich, Helle D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1258175/
https://www.ncbi.nlm.nih.gov/pubmed/16224103
http://dx.doi.org/10.1093/nar/gki902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1258175/
https://www.ncbi.nlm.nih.gov/pubmed/16224103
http://dx.doi.org/10.1093/nar/gki902

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