Atomic force microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in a cooperative fashion

Type IB DNA topoisomerases cleave and rejoin one strand of the DNA duplex, allowing for the removal of supercoils generated during replication and transcription. In addition, electron microscopy of cellular and viral TopIB–DNA complexes has suggested that the enzyme promotes long-range DNA–DNA cross...

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Detalles Bibliográficos
Autores principales: Moreno-Herrero, Fernando, Holtzer, Laurent, Koster, Daniel A., Shuman, Stewart, Dekker, Cees, Dekker, Nynke H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1258176/
https://www.ncbi.nlm.nih.gov/pubmed/16237128
http://dx.doi.org/10.1093/nar/gki906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1258176/
https://www.ncbi.nlm.nih.gov/pubmed/16237128
http://dx.doi.org/10.1093/nar/gki906

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