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Phylogenetic analysis of eIF4E-family members

BACKGROUND: Translation initiation in eukaryotes involves the recruitment of mRNA to the ribosome which is controlled by the translation factor eIF4E. eIF4E binds to the 5'-m(7)Gppp cap-structure of mRNA. Three dimensional structures of eIF4Es bound to cap-analogues resemble 'cupped-hands&...

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Detalles Bibliográficos
Autores principales: Joshi, Bhavesh, Lee, Kibwe, Maeder, Dennis L, Jagus, Rosemary
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1260017/
https://www.ncbi.nlm.nih.gov/pubmed/16191198
http://dx.doi.org/10.1186/1471-2148-5-48