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Regional differences in APD restitution can initiate wavebreak and re-entry in cardiac tissue: A computational study

BACKGROUND: Regional differences in action potential duration (APD) restitution in the heart favour arrhythmias, but the mechanism is not well understood. METHODS: We simulated a 150 × 150 mm 2D sheet of cardiac ventricular tissue using a simplified computational model. We investigated wavebreak and...

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Detalles Bibliográficos
Autores principales: Clayton, Richard H, Taggart, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1261529/
https://www.ncbi.nlm.nih.gov/pubmed/16174290
http://dx.doi.org/10.1186/1475-925X-4-54