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Systemic alendronate prevents resorption of necrotic bone during revascularization. A bone chamber study in rats

BACKGROUND: Avascular necrosis of bone (osteonecrosis) can cause structural failure and subsequent deformation, leading to joint dysfunction and pain. Structural failure is the result of resorption of necrotic bone during revascularization, before new bone has formed or consolidated enough for loadb...

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Detalles Bibliográficos
Autores principales: Åstrand, Jörgen, Aspenberg, Per
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC126216/
https://www.ncbi.nlm.nih.gov/pubmed/12165099
http://dx.doi.org/10.1186/1471-2474-3-19