Modeling T Cell Antigen Discrimination Based on Feedback Control of Digital ERK Responses

T-lymphocyte activation displays a remarkable combination of speed, sensitivity, and discrimination in response to peptide–major histocompatibility complex (pMHC) ligand engagement of clonally distributed antigen receptors (T cell receptors or TCRs). Even a few foreign pMHCs on the surface of an ant...

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Detalles Bibliográficos
Autores principales: Altan-Bonnet, Grégoire, Germain, Ronald N
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262625/
https://www.ncbi.nlm.nih.gov/pubmed/16231973
http://dx.doi.org/10.1371/journal.pbio.0030356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262625/
https://www.ncbi.nlm.nih.gov/pubmed/16231973
http://dx.doi.org/10.1371/journal.pbio.0030356

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