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Epigenetic predisposition to expression of TIMP1 from the human inactive X chromosome
BACKGROUND: X inactivation in mammals results in the transcriptional silencing of an X chromosome in females, and this inactive X acquires many of the epigenetic features of silent chromatin. However, not all genes on the inactive X are silenced, and we have examined the TIMP1 gene, which has variab...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262707/ https://www.ncbi.nlm.nih.gov/pubmed/16194278 http://dx.doi.org/10.1186/1471-2156-6-48 |