Prediction of "hot spots" of aggregation in disease-linked polypeptides

BACKGROUND: The polypeptides involved in amyloidogenesis may be globular proteins with a defined 3D-structure or natively unfolded proteins. The first class includes polypeptides such as β2-microglobulin, lysozyme, transthyretin or the prion protein, whereas β-amyloid peptide, amylin or α-synuclein...

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Detalles Bibliográficos
Autores principales: de Groot, Natalia Sánchez, Pallarés, Irantzu, Avilés, Francesc X, Vendrell, Josep, Ventura, Salvador
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262731/
https://www.ncbi.nlm.nih.gov/pubmed/16197548
http://dx.doi.org/10.1186/1472-6807-5-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262731/
https://www.ncbi.nlm.nih.gov/pubmed/16197548
http://dx.doi.org/10.1186/1472-6807-5-18

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