Regulation of IκBα expression involves both NF-κB and the MAP kinase signaling pathways

IκBα is an inhibitor of the nuclear transcription factor NF-κB. Binding of IκBα to NF-κB inactivates the transcriptional activity of NF-κB. Expression of IκBα itself is regulated by NF-κB, which provides auto-regulation of this signaling pathway. Here we present a mouse model for monitoring in vivo...

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Detalles Bibliográficos
Autores principales: Zhang, Ning, Ahsan, Muhammad H, Zhu, Lingyun, Sambucetti, Lidia C, Purchio, Anthony F, West, David B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262753/
https://www.ncbi.nlm.nih.gov/pubmed/16207380
http://dx.doi.org/10.1186/1476-9255-2-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262753/
https://www.ncbi.nlm.nih.gov/pubmed/16207380
http://dx.doi.org/10.1186/1476-9255-2-10

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