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Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors)

BACKGROUND: The nuclear hormone receptor (NR) superfamily complement in humans is composed of 48 genes with diverse roles in metabolic homeostasis, development, and detoxification. In general, NRs are strongly conserved between vertebrate species, and few examples of molecular adaptation (positive s...

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Detalles Bibliográficos
Autores principales: Krasowski, Matthew D, Yasuda, Kazuto, Hagey, Lee R, Schuetz, Erin G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262763/
https://www.ncbi.nlm.nih.gov/pubmed/16197547
http://dx.doi.org/10.1186/1478-1336-3-2