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Use of altered-specificity binding Oct-4 suggests an absence of pluripotent cell-specific cofactor usage
Oct-4 is a POU domain transcription factor that is critical for maintaining pluripotency and for stem cell renewal. Previous studies suggest that transcription regulation by Oct-4 at particular enhancers requires the input of a postulated E1A-like cofactor that is specific to pluripotent cells. Howe...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266064/ https://www.ncbi.nlm.nih.gov/pubmed/16243786 http://dx.doi.org/10.1093/nar/gki907 |