Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents

The proximal promoter region of the human vascular endothelial growth factor (VEGF) gene contains a polypurine/polypyrimidine tract that serves as a multiple binding site for Sp1 and Egr-1 transcription factors. This tract contains a guanine-rich sequence consisting of four runs of three or more con...

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Detalles Bibliográficos
Autores principales: Sun, Daekyu, Guo, Kexiao, Rusche, Jadrian J., Hurley, Laurence H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266068/
https://www.ncbi.nlm.nih.gov/pubmed/16239639
http://dx.doi.org/10.1093/nar/gki917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266068/
https://www.ncbi.nlm.nih.gov/pubmed/16239639
http://dx.doi.org/10.1093/nar/gki917

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