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Selection of optimal oligonucleotide probes for microarrays using multiple criteria, global alignment and parameter estimation
The oligonucleotide specificity for microarray hybridization can be predicted by its sequence identity to non-targets, continuous stretch to non-targets, and/or binding free energy to non-targets. Most currently available programs only use one or two of these criteria, which may choose ‘false’ speci...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266071/ https://www.ncbi.nlm.nih.gov/pubmed/16246912 http://dx.doi.org/10.1093/nar/gki914 |