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Transgene-induced CCWGG methylation does not alter CG methylation patterning in human kidney cells

Several reports suggest that C(m)CWGG methylation tends not to co-exist with (m)CG methylation in human cells. We have asked whether or not methylation at CCWGG sites can influence CG methylation. DNA from cells expressing an M.EcoRII–GFP fusion was actively methylated at CCWGG sites. CG methylation...

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Detalles Bibliográficos
Autores principales: Shevchuk, Taras, Kretzner, Leo, Munson, Kristofer, Axume, John, Clark, Jarrod, Dyachenko, Olga V., Caudill, Marie, Buryanov, Yaroslav, Smith, Steven S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266073/
https://www.ncbi.nlm.nih.gov/pubmed/16246913
http://dx.doi.org/10.1093/nar/gki920