Rearranging the centromere of the human Y chromosome with φC31 integrase

We have investigated the ability of the integrase from the Streptomyces φC31 ‘phage to either delete or invert 1 Mb of DNA around the centromere of the human Y chromosome in chicken DT40 hybrid somatic cells. Reciprocal and conservative site-specific recombination was observed in 54% of cells expres...

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Detalles Bibliográficos
Autores principales: Malla, Sunir, Dafhnis-Calas, Felix, Brookfield, John F. Y., Smith, Margaret C. M., Brown, William R. A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266074/
https://www.ncbi.nlm.nih.gov/pubmed/16246911
http://dx.doi.org/10.1093/nar/gki922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266074/
https://www.ncbi.nlm.nih.gov/pubmed/16246911
http://dx.doi.org/10.1093/nar/gki922

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