Anthrax Lethal Toxin-Mediated Killing of Human and Murine Dendritic Cells Impairs the Adaptive Immune Response

Many pathogens have acquired strategies to combat the immune response. Bacillus anthracis interferes with host defenses by releasing anthrax lethal toxin (LT), which inactivates mitogen-activated protein kinase pathways, rendering dendritic cells (DCs) and T lymphocytes nonresponsive to immune stimu...

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Detalles Bibliográficos
Autores principales: Alileche, Abdelkrim, Serfass, Evan R, Muehlbauer, Stefan M, Porcelli, Steven A, Brojatsch, Jürgen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266308/
https://www.ncbi.nlm.nih.gov/pubmed/16254597
http://dx.doi.org/10.1371/journal.ppat.0010019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266308/
https://www.ncbi.nlm.nih.gov/pubmed/16254597
http://dx.doi.org/10.1371/journal.ppat.0010019

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