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DBR1 siRNA inhibition of HIV-1 replication

BACKGROUND: HIV-1 and all retroviruses are related to retroelements of simpler organisms such as the yeast Ty elements. Recent work has suggested that the yeast retroelement Ty1 replicates via an unexpected RNA lariat intermediate in cDNA synthesis. The putative genomic RNA lariat intermediate is fo...

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Detalles Bibliográficos
Autores principales: Ye, Ying, De Leon, Jessica, Yokoyama, Noriko, Naidu, Yathi, Camerini, David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266399/
https://www.ncbi.nlm.nih.gov/pubmed/16232320
http://dx.doi.org/10.1186/1742-4690-2-63