Protein–DNA binding specificity predictions with structural models

Protein–DNA interactions play a central role in transcriptional regulation and other biological processes. Investigating the mechanism of binding affinity and specificity in protein–DNA complexes is thus an important goal. Here we develop a simple physical energy function, which uses electrostatics,...

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Detalles Bibliográficos
Autores principales: Morozov, Alexandre V., Havranek, James J., Baker, David, Siggia, Eric D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270944/
https://www.ncbi.nlm.nih.gov/pubmed/16246914
http://dx.doi.org/10.1093/nar/gki875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270944/
https://www.ncbi.nlm.nih.gov/pubmed/16246914
http://dx.doi.org/10.1093/nar/gki875

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