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Protein–DNA binding specificity predictions with structural models
Protein–DNA interactions play a central role in transcriptional regulation and other biological processes. Investigating the mechanism of binding affinity and specificity in protein–DNA complexes is thus an important goal. Here we develop a simple physical energy function, which uses electrostatics,...
Autores principales: | Morozov, Alexandre V., Havranek, James J., Baker, David, Siggia, Eric D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270944/ https://www.ncbi.nlm.nih.gov/pubmed/16246914 http://dx.doi.org/10.1093/nar/gki875 |
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