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Cytological profiling: providing more haystacks for chemists' needles

Conventional high-throughput 'chemical genetic' screening seeks to identify small-molecule inhibitors of a specific protein or pathway. A recent study describes how unbiased screening of cellular morphology, followed by affinity purification to identify targets of compounds with interestin...

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Detalles Bibliográficos
Autores principales: Lorang, Janet, King, Randall W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1273624/
https://www.ncbi.nlm.nih.gov/pubmed/16086858
http://dx.doi.org/10.1186/gb-2005-6-8-228