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Elevated expression of CD30 in adult T-cell leukemia cell lines: possible role in constitutive NF-κB activation

BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-1) is associated with the development of adult T-cell leukemia (ATL). HTLV-1 encoded Tax1 oncoprotein activates the transcription of genes involved in cell growth and anti-apoptosis through the NF-κB pathway, and is thought to play a critical role...

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Detalles Bibliográficos
Autores principales: Higuchi, Masaya, Matsuda, Takehiro, Mori, Naoki, Yamada, Yasuaki, Horie, Ryouichi, Watanabe, Toshiki, Takahashi, Masahiko, Oie, Masayasu, Fujii, Masahiro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1274245/
https://www.ncbi.nlm.nih.gov/pubmed/15876358
http://dx.doi.org/10.1186/1742-4690-2-29