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Elevated expression of CD30 in adult T-cell leukemia cell lines: possible role in constitutive NF-κB activation
BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-1) is associated with the development of adult T-cell leukemia (ATL). HTLV-1 encoded Tax1 oncoprotein activates the transcription of genes involved in cell growth and anti-apoptosis through the NF-κB pathway, and is thought to play a critical role...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1274245/ https://www.ncbi.nlm.nih.gov/pubmed/15876358 http://dx.doi.org/10.1186/1742-4690-2-29 |