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ProfNet, a method to derive profile-profile alignment scoring functions that improves the alignments of distantly related proteins

BACKGROUND: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distribution of amino acids and substitution tables either when constructing the profiles or in the scoring. This makes the methods...

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Detalles Bibliográficos
Autores principales: Ohlson, Tomas, Elofsson, Arne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1274300/
https://www.ncbi.nlm.nih.gov/pubmed/16225676
http://dx.doi.org/10.1186/1471-2105-6-253