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ProfNet, a method to derive profile-profile alignment scoring functions that improves the alignments of distantly related proteins
BACKGROUND: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distribution of amino acids and substitution tables either when constructing the profiles or in the scoring. This makes the methods...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1274300/ https://www.ncbi.nlm.nih.gov/pubmed/16225676 http://dx.doi.org/10.1186/1471-2105-6-253 |