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Insulin Promoter Factor 1 variation is associated with type 2 diabetes in African Americans

BACKGROUND: Defective insulin secretion is a key defect in the pathogenesis of type 2 diabetes (T2DM). The β-cell specific transcription factor, insulin promoter factor 1 gene (IPF1), is essential to pancreatic development and the maintenance of β-cell mass. We hypothesized that regulatory or coding...

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Detalles Bibliográficos
Autores principales: Karim, Mohammad A, Wang, Xiaoqin, Hale, Terri C, Elbein, Steven C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1274317/
https://www.ncbi.nlm.nih.gov/pubmed/16229747
http://dx.doi.org/10.1186/1471-2350-6-37