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Position of the fluorescent label is a crucial factor determining signal intensity in microarray hybridizations
A key issue in applications of short oligonucleotide-based microarrays is how to design specific probes with high sensitivity. Some details of the factors affecting microarray hybridization remain unclear, hampering a reliable quantification of target nucleic acids. We have evaluated the effect of t...
Autores principales: | Zhang, Lei, Hurek, Thomas, Reinhold-Hurek, Barbara |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1275592/ https://www.ncbi.nlm.nih.gov/pubmed/16257977 http://dx.doi.org/10.1093/nar/gni156 |
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