A colorimetric method for point mutation detection using high-fidelity DNA ligase

The present study reported proof-of-principle for a genotyping assay approach that can detect single nucleotide polymorphisms (SNPs) through the gold nanoparticle assembly and the ligase reaction. By incorporating the high-fidelity DNA ligase (Tth DNA ligase) into the allele-specific ligation-based...

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Detalles Bibliográficos
Autores principales: Li, Jishan, Chu, Xia, Liu, Yali, Jiang, Jian-Hui, He, Zhimin, Zhang, Zhiwei, Shen, Guoli, Yu, Ru-Qin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1275593/
https://www.ncbi.nlm.nih.gov/pubmed/16257979
http://dx.doi.org/10.1093/nar/gni163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1275593/
https://www.ncbi.nlm.nih.gov/pubmed/16257979
http://dx.doi.org/10.1093/nar/gni163

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