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ASPIC: a novel method to predict the exon-intron structure of a gene that is optimally compatible to a set of transcript sequences

BACKGROUND: Currently available methods to predict splice sites are mainly based on the independent and progressive alignment of transcript data (mostly ESTs) to the genomic sequence. Apart from often being computationally expensive, this approach is vulnerable to several problems – hence the need t...

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Detalles Bibliográficos
Autores principales: Bonizzoni, Paola, Rizzi, Raffaella, Pesole, Graziano
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1276783/
https://www.ncbi.nlm.nih.gov/pubmed/16207377
http://dx.doi.org/10.1186/1471-2105-6-244