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Statistical distributions of optimal global alignment scores of random protein sequences

BACKGROUND: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function underlying the optimal global alignments has not been completely determined. RESULTS: In this study, random and real but un...

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Detalles Bibliográficos
Autores principales: Pang, Hongxia, Tang, Jiaowei, Chen, Su-Shing, Tao, Shiheng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1276786/
https://www.ncbi.nlm.nih.gov/pubmed/16225696
http://dx.doi.org/10.1186/1471-2105-6-257