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Modeling the signaling endosome hypothesis: Why a drive to the nucleus is better than a (random) walk

BACKGROUND: Information transfer from the plasma membrane to the nucleus is a universal cell biological property. Such information is generally encoded in the form of post-translationally modified protein messengers. Textbook signaling models typically depend upon the diffusion of molecular signals...

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Detalles Bibliográficos
Autor principal: Howe, Charles L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1276819/
https://www.ncbi.nlm.nih.gov/pubmed/16236165
http://dx.doi.org/10.1186/1742-4682-2-43