Structure–function analysis of yeast RNA debranching enzyme (Dbr1), a manganese-dependent phosphodiesterase

Saccharomyces cerevisiae Dbr1 is a 405-amino acid RNA debranching enzyme that cleaves the 2′-5′ phosphodiester bonds of the lariat introns formed during pre-mRNA splicing. Debranching appears to be a rate-limiting step for the turnover of intronic RNA, insofar as the steady-state levels of lariat in...

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Detalles Bibliográficos
Autores principales: Khalid, M. Fahad, Damha, Masad J., Shuman, Stewart, Schwer, Beate
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1278944/
https://www.ncbi.nlm.nih.gov/pubmed/16275784
http://dx.doi.org/10.1093/nar/gki934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1278944/
https://www.ncbi.nlm.nih.gov/pubmed/16275784
http://dx.doi.org/10.1093/nar/gki934

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