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DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4–Not complex

Genetic experiments have indicated a role for the Ccr4–Not complex in the response to hydroxyurea (HU) induced replication stress and ionizing radiation in yeast. This response includes transcriptional induction of the four genes constituting the ribonucleotide reductase (RNR) enzymatic complex, RNR...

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Detalles Bibliográficos
Autores principales: Mulder, Klaas W., Winkler, G. Sebastiaan, Timmers, H. Th. Marc
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1278945/
https://www.ncbi.nlm.nih.gov/pubmed/16275785
http://dx.doi.org/10.1093/nar/gki938