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An analysis of the feasibility of short read sequencing

Several methods for ultra high-throughput DNA sequencing are currently under investigation. Many of these methods yield very short blocks of sequence information (reads). Here we report on an analysis showing the level of genome sequencing possible as a function of read length. It is shown that re-s...

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Detalles Bibliográficos
Autores principales: Whiteford, Nava, Haslam, Niall, Weber, Gerald, Prügel-Bennett, Adam, Essex, Jonathan W., Roach, Peter L., Bradley, Mark, Neylon, Cameron
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1278949/
https://www.ncbi.nlm.nih.gov/pubmed/16275781
http://dx.doi.org/10.1093/nar/gni170