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Second-Hand Smoke–Induced Cardiac Fibrosis Is Related to the Fas Death Receptor Apoptotic Pathway without Mitochondria-Dependent Pathway Involvement in Rats

Exposure to environmental tobacco smoke has been epidemiologically linked to heart disease among nonsmokers. However, the molecular mechanism behind the pathogenesis of cardiac disease is unknown. In this study, we found that Wistar rats, exposed to tobacco cigarette smoke at doses of 5, 10, or 15 c...

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Detalles Bibliográficos
Autores principales: Kuo, Wei-Wen, Wu, Chieh-Hsi, Lee, Shin-Da, Lin, James A., Chu, Chia-Yih, Hwang, Jin-Ming, Ueng, Kwo-Chang, Chang, Mu-Hsin, Yeh, Yu-Lan, Wang, Chau-Jong, Liu, Jer-Yuh, Huang, Chih-Yang
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1281278/
https://www.ncbi.nlm.nih.gov/pubmed/16203245
http://dx.doi.org/10.1289/ehp.7479