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Molecular Characterization of Thyroid Toxicity: Anchoring Gene Expression Profiles to Biochemical and Pathologic End Points

Organic iodides have been shown to induce thyroid hypertrophy and increase alterations in colloid in rats, although the mechanism involved in this toxicity is unclear. To evaluate the effect that free iodide has on thyroid toxicity, we exposed rats for 2 weeks by daily gavage to sodium iodide (NaI)....

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Detalles Bibliográficos
Autores principales: Glatt, Christine M., Ouyang, Ming, Welsh, William, Green, John W., Connor, John O, Frame, Steven R., Everds, Nancy E., Poindexter, Greg, Snajdr, Suzanne, Delker, Don A.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1281279/
https://www.ncbi.nlm.nih.gov/pubmed/16203246
http://dx.doi.org/10.1289/ehp.7690