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Molecular Characterization of Thyroid Toxicity: Anchoring Gene Expression Profiles to Biochemical and Pathologic End Points
Organic iodides have been shown to induce thyroid hypertrophy and increase alterations in colloid in rats, although the mechanism involved in this toxicity is unclear. To evaluate the effect that free iodide has on thyroid toxicity, we exposed rats for 2 weeks by daily gavage to sodium iodide (NaI)....
Autores principales: | Glatt, Christine M., Ouyang, Ming, Welsh, William, Green, John W., Connor, John O, Frame, Steven R., Everds, Nancy E., Poindexter, Greg, Snajdr, Suzanne, Delker, Don A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1281279/ https://www.ncbi.nlm.nih.gov/pubmed/16203246 http://dx.doi.org/10.1289/ehp.7690 |
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