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Functional Interactions Between A' Helices in the C-linker of Open CNG Channels

Cyclic nucleotide-gated (CNG) channels are nonselective cation channels that are activated by the direct binding of the cyclic nucleotides cAMP and cGMP. The region linking the last membrane-spanning region (S6) to the cyclic nucleotide binding domain in the COOH terminus, termed the C-linker, has b...

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Detalles Bibliográficos
Autores principales: Hua, Li, Gordon, Sharona E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1282461/
https://www.ncbi.nlm.nih.gov/pubmed/15738051
http://dx.doi.org/10.1085/jgp.200409187