The role of c-kit and imatinib mesylate in uveal melanoma

BACKGROUND: Uveal melanoma (UM) is the most common primary intraocular tumor in adults, leading to metastasis in 40% of the cases and ultimately to death in 10 years, despite local and/or systemic treatment. The c-kit protein (CD117) is a membrane-bound tyrosine kinase receptor and its overexpressio...

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Detalles Bibliográficos
Autores principales: Pereira, Patricia Rusa, Odashiro, Alexandre Nakao, Marshall, Jean Claude, Correa, Zelia Maria, Belfort, Rubens, Burnier, Miguel N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1282581/
https://www.ncbi.nlm.nih.gov/pubmed/16236162
http://dx.doi.org/10.1186/1477-3163-4-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1282581/
https://www.ncbi.nlm.nih.gov/pubmed/16236162
http://dx.doi.org/10.1186/1477-3163-4-19

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