Impaired DNA Replication within Progenitor Cell Pools Promotes Leukemogenesis

Impaired cell cycle progression can be paradoxically associated with increased rates of malignancies. Using retroviral transduction of bone marrow progenitors followed by transplantation into mice, we demonstrate that inhibition of hematopoietic progenitor cell proliferation impairs competition, pro...

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Detalles Bibliográficos
Autores principales: Bilousova, Ganna, Marusyk, Andriy, Porter, Christopher C, Cardiff, Robert D, DeGregori, James
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283331/
https://www.ncbi.nlm.nih.gov/pubmed/16277552
http://dx.doi.org/10.1371/journal.pbio.0030401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283331/
https://www.ncbi.nlm.nih.gov/pubmed/16277552
http://dx.doi.org/10.1371/journal.pbio.0030401

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