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Impaired DNA Replication within Progenitor Cell Pools Promotes Leukemogenesis
Impaired cell cycle progression can be paradoxically associated with increased rates of malignancies. Using retroviral transduction of bone marrow progenitors followed by transplantation into mice, we demonstrate that inhibition of hematopoietic progenitor cell proliferation impairs competition, pro...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283331/ https://www.ncbi.nlm.nih.gov/pubmed/16277552 http://dx.doi.org/10.1371/journal.pbio.0030401 |