Ancient and Recent Positive Selection Transformed Opioid cis-Regulation in Humans

Changes in the cis-regulation of neural genes likely contributed to the evolution of our species' unique attributes, but evidence of a role for natural selection has been lacking. We found that positive natural selection altered the cis-regulation of human prodynorphin, the precursor molecule f...

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Detalles Bibliográficos
Autores principales: Rockman, Matthew V, Hahn, Matthew W, Soranzo, Nicole, Zimprich, Fritz, Goldstein, David B, Wray, Gregory A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283535/
https://www.ncbi.nlm.nih.gov/pubmed/16274263
http://dx.doi.org/10.1371/journal.pbio.0030387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283535/
https://www.ncbi.nlm.nih.gov/pubmed/16274263
http://dx.doi.org/10.1371/journal.pbio.0030387

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