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Ancient and Recent Positive Selection Transformed Opioid cis-Regulation in Humans
Changes in the cis-regulation of neural genes likely contributed to the evolution of our species' unique attributes, but evidence of a role for natural selection has been lacking. We found that positive natural selection altered the cis-regulation of human prodynorphin, the precursor molecule f...
Autores principales: | Rockman, Matthew V, Hahn, Matthew W, Soranzo, Nicole, Zimprich, Fritz, Goldstein, David B, Wray, Gregory A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283535/ https://www.ncbi.nlm.nih.gov/pubmed/16274263 http://dx.doi.org/10.1371/journal.pbio.0030387 |
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