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Securin Is Not Required for Chromosomal Stability in Human Cells

Abnormalities of chromosome number are frequently observed in cancers. The mechanisms regulating chromosome segregation in human cells are therefore of great interest. Recently it has been reported that human cells without an hSecurin gene lose chromosomes at a high frequency. Here we show that, aft...

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Detalles Bibliográficos
Autores principales: Pfleghaar, Katrin, Heubes, Simone, Cox, Jürgen, Stemmann, Olaf, Speicher, Michael R
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1287505/
https://www.ncbi.nlm.nih.gov/pubmed/16292982
http://dx.doi.org/10.1371/journal.pbio.0030416